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Both MEPH and nor-MEPH were being detected in all substrates, with the highest degrees detected in lungs. Suggest brain: serum ratios have been 1:one.19 (MEPH) and 1:one.ninety one (nor-MEPH), highest concentrations were being observed at 30 min; at two and four h after administration, nor-MEPH concentrations had been greater when compared with the